New St. Mary's Hospital - Jefferson City

SSM Health St. Mary's Hospital - Jefferson City

​​​​​​​​​2505 Mission Drive
Jefferson City, MO 65109
​Map & Directions

​​Please note that many online mapping and GPS systems have not updated with our new address above. St. Mary’s Hospital - Jefferson City's new location is at Highway 179 and Mission Drive exit, which is north of Highway 54 and south of Highway 50. If you have any issues, you can dial the main hospital line at 573-681-3000.

Take an online tour of St. Mary's Hospital - Jefferson City
​​Our Visitor Parking structure is located across from our main entrance and can be accessed by taking the first right turn at the round-about. For visitors to our outpatient and Health P​laza services, there is surface parking located near the  Health Plaza entrance. To access the Health Plaza parking, take the second turn at the round-about onto Rolling Hills Drive. There is dedicated parking for Emergency Room visitors, which is located in front of the emergency room entrance. To access, take the second turn at the round-about onto Rolling Hills Drive.  

For your convenience, there is covered drop-off and pick-up at each of our three entrances.

View or print our Campus Map.

About the Hospital and Services 
St. Mary’s Hospital - Jefferson City is a 154-bed, full-service community hospital located in Missouri’s state capital. The hospital features a dedicated inpatient pediatric unit, a Wound Center and Outpatient Treatment Center​. Other services offered at the hospital include emergency services, cardiology, orthopedic care, cancer care, outpatient surgical services, maternity care and women’s health. The hospital moved to a new, state-of-the-art building in November 2014. Learn more about the patient-centered design and features of the new facility. 

St. Mar​​y’s Hospital - Jefferson City opened in 1905 as part of a faith-based healing ministry of the Franciscan Sisters of Mary

Connect Online with St. Mary's Hospital - Jefferson City​

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    • I am age 35 or older.
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    • I was not diagnosed with breast cancer within the last three years.
    • I have not breast fed within the last six months.
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